Thymidylate kinase 3D structures

3D Structures of thymidylate kinase3D Structures of thymidylate kinase

Updated on 25-December-2023 - For a general description of the protein see Thymidylate kinase

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• Thymidylate kinase
  • 2cck, 4f4i – SaTMK – Staphylococcus aureus
    
  • 2pbr, 4s2e, 5h5b – AaTMK – Aquifex aeolicus
    
  • 5xb5, 5xbh – AaTMK (mutant)
    
  • 2plr – TMK – Sulfolobus tokodaii
    
  • 3ld9 – TMK – Ehrlichia chafeensis
    
  • 3v9p – TMK – Burkholderia thailandensis
    
  • 3uwk, 3uwo – PaTMK – Pseudomonas aeruginosa
    
  • 5x7j, 5xak, 5xt8 – TtTMK – Thermus thermophilus
    
  • 5x8d, 5x8j, 5x8k, 5x8v, 5x98, 5x99, 5xal – TtTMK (mutant)
    
• Thymidylate kinase complex with HIV prodrug AZT derivative
  • 1e98, 1e99, 1e9d – hTMK (mutant) + AZTP + ADP - human
    
  • 2tmk – yTMK + AZTP
    
  • 4eaq – SaTMK + AZTP
    
  • 4gmd – PaTMK + AZTP
    
  • 4tmk, 5tmp – TMK + AZTP – Escherichia coli
    
  • 1w2h – MtTMK + AZTP - Mycobacterium tuberculosis
    
• Thymidylate kinase complex with one nucleotide
  • 1tmk – yTMK + dTMP - yeast
    
  • 2v54 – VvTMK + TDP – Vaccinia virus
    
  • 2w0s – VvTMK + brivudin-MP
    
  • 4e5u – PaTMK + dTMP
    
  • 3uxm, 4esh – PaTMK + deoxy thymidine derivative
    
  • 2ccg, 2ccj, 4dwj – SaTMK + dTMP
    
  • 1g3u, 1gsi, 1n5i, 1n5k – MtTMK + dTMP
    
  • 1w2g – MtTMK + thymidine
    
  • 1gtv – MtTMK + TDP
    
  • 1mrs – MtTMK + UMP derivative
    
  • 2yof, 2yog, 2yoh - PfTMK + thymidine analog – Plasmodium falciparum
    
  • 5xai – AaTMK + TMP
    
  • 5x86 – TtTMK + dTMP
    
  • 5x8a – TtTMK + ATP
    
  • 7fgq – TMK + TMP – Brugia malayi
    
• Thymidylate kinase complex with two nucleotides
  • 1e2d, 1e2e, 1e2f, 1e9e, 1e9f – hTMK (mutant) + ADP + dTMP
    
  • 1e2q, 1e9f – hTMK (mutant) + ADP + dTMP
    
  • 1e9b – hTMK (mutant) + azido-TMP + APPNP
    
  • 1e9c – hTMK (mutant) + dTMP + APPNP
    
  • 1nmx – hTMK (mutant) + F-TMP + ADP
    
  • 1nmy, 1nn0, 1nnz, 1nn1, 1nn3, 1nn5, 1nmz – hTMK (mutant) + dTMP derivative + APPNP
    
  • 2xx3 – hTMK + dTMP derivative + ADP
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  • 4edh – PaTMK + ADP + dTMP
    
  • 1n5j – MtTMK + TDP + TTP
    
  • 1n5l – MtTMK + TDP + dTMP
    
  • 3hjn – TMK + ADP + TDP – Thermotoga maritima
    
  • 3lv8 – VcTMK + ADP + dTMP + TDP – Vibrio cholerae
    
  • 3n2i – VcTMK + thymidine + thymidine deoxy-thymidine
    
  • 4s35 – AaTMK + dTMP + AMPPCP
    
  • 5h56 – AaTMK + dTDP + ADP
    
  • 5xb2, 5xb3 – AaTMK + dTMP + ADP
    
  • 5h5k – AaTMK + CMP + ATP
    
  • 5uiv - TMK + TMP + ADP – Candida albicans
    
  • 5x8b – TtTMK + TMP + ADP + ATP
    
  • 5zax – TtTMK + TMP + ADP + TDP
    
  • 5zb0 – TtTMK + ADP + TDP
    
  • 5zb4 – TtTMK + ADP + TMP
    
  • 5x8c – TtTMK + dTMP + AMPPCP
    
• Other thymidylate kinase binary complexes
  • 4gfd, 4hlc, 4hld, 4hej, 4hdc – SaTMK + antibacterial drug
    
  • 4gsy, 4qg7, 4xwa – SaTMK + inhibitor
    
  • 4qg7, 4qgf, 4qgg, 4qgh, 4qga – SaTMK (mutant) + inhibitor
    
  • 4mqb – SaTMK + MES
    
  • 4unp, 4unq, 4unn, 4unr, 4uns, 5nr7, 5nrn, 5nrq, 5nq5, 6yt1 – MtTMK + inhibitor
    
• Thymidylate kinase complex with bisubstrate inhibitor
  • 1mrn – MtTMK + TP5A
    
  • 3tmk – yTMK + TP5A
    
  • 1e9a – hTMK (mutant) + azido-TP5A + ADP