TMK from S.aureus in complex with the Piperidinyl Thymine class inhibitor with a C5 ethyl-amineTMK from S.aureus in complex with the Piperidinyl Thymine class inhibitor with a C5 ethyl-amine

Structural highlights

4xwa is a 2 chain structure with sequence from Staphylococcus aureus subsp. aureus Mu3. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.89Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

KTHY_STAA1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

See Also

4xwa, resolution 1.89Å

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OCA