3vx8

Crystal structure of Arabidopsis thaliana Atg7NTD-Atg3 complexCrystal structure of Arabidopsis thaliana Atg7NTD-Atg3 complex

Structural highlights 3vx8 is a 4 chain structure with sequence from Arath. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Related: 3vx6, 3vx7 Gene: ATG7, APG7, At5g45900, K15I22.10 (ARATH), ATG3, APG3, At5g61500, K11J9.3 (ARATH) Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [ATG7_ARATH] E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes. Involved in the senescence process. [ATG3_ARATH] E2 conjugating enzyme responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8. This step is required for the membrane association of ATG8. The formation of the ATG8-phosphatidylethanolamine conjugate is essential for autophagy and for the cytoplasm to vacuole transport (Cvt). See Also Autophagy-related protein 3D structures

spinqualitylabelsall models 3vx8, resolution 3.11Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image