1pft
N-TERMINAL DOMAIN OF TFIIB, NMRN-TERMINAL DOMAIN OF TFIIB, NMR
Structural highlights
Function[TF2B_PYRFU] Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). Evolutionary ConservationCheck, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. Publication Abstract from PubMedThe three-dimensional structure of the N-terminal domain of an archaeal TFIIB, which has high sequence homology with eucaryal analogues, is strikingly similar to that of the C-terminal zinc ribbon of the eucaryal transcription elongation factor TFIIB. The N-terminal domain of TFIIB from Pyrococcus furiosus forms a zinc ribbon.,Zhu W, Zeng Q, Colangelo CM, Lewis M, Summers MF, Scott RA Nat Struct Biol. 1996 Feb;3(2):122-4. PMID:8564536[1] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See AlsoReferences |
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