RNA ligase

RNA ligase (LigR) is an enzyme which ligates two ribonucleotide chains using ATP and producing AMP, diphosphate and the ligated ribonucleotide chain. See more details in T4 RNA ligase 2 (Rnl2) and Ligases.

spinqualitylabelsall models Se-Met RNA ligase (PDB code 1vgj) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

3D Structures of RNA ligase3D Structures of RNA ligase

Updated on 27-October-2020

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• RNA ligase
  • 2c5u – T4LigR 1 RNA-binding domain - Enterobacteria phage T4
    
  • 1s68 - T4LigR 2 N-terminal
    
  • 1vgj, 1vdx – PyLigR – Pyrococcus horikoshii
    
  • 2vug – LigR – Pyrococcus abyssi
    
  • 1xdn – LigR 1 editing – Trypanosoma brucei
    
  • 1iuh – LigR 2’-5’ – Thermus thermophilus
    
  • 5cot – aLigR – amoeba
    
  • 6vt0, 6vt1, 6vt3, 6vt4, 6vt5, 6vtg, 5cov – aLigR (mutant)
    
• RNA ligase complex
  • 5tt6 – T4LigR 1 + ATP
    
  • 2hvr, 2hvs – T4LigR 2 + DNA + nucleotide
    
  • 2hvq - T4LigR 2 + adenosine derivative
    
  • 4qak - LigR 2’-5’ + AMP – Escherichia coli
    
  • 5cou, 6vt6, 6vt8, 6vt9, 6vtb, 6vtd – aLigR (mutant) + ATP
    
  • 6vte – aLigR (mutant) + AMP
    
  • 6vtf – aLigR + pyrophosphate
    
  • 5d1o, 5d1p – LigR ATP-dependent + ATP – Methanothermobacter thermautotrophicus
    
  • 4isz – PhLigR RtcB + GTP + Mn
    
  • 4dwq, 4it0 – PhLigR RtcB + GMP + Mn
    
  • 4isj, 4dwr – PhLigR RtcB + Mn