RNA ligase

RNA ligase (LigR) is an enzyme which ligates two ribonucleotide chains using ATP and producing AMP, diphosphate and the ligated ribonucleotide chain. RNA ligase RtcB joins 2',3'-cyclic phosphate and 5'-OH ends. See more details in T4 RNA ligase 2 (Rnl2) and Ligases.

spinqualitylabelsall models Se-Met RNA ligase (PDB code 1vgj) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

3D Structures of RNA ligase3D Structures of RNA ligase

Updated on 05-November-2023

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• RNA ligase
  • 2c5u – T4LigR 1 RNA-binding domain - Enterobacteria phage T4
    
  • 1s68 - T4LigR 2 N-terminal
    
  • 1vgj, 1vdx – PhLigR – Pyrococcus horikoshii
    
  • 8dcg – PhLigR RtcB
    
  • 2vug – LigR – Pyrococcus abyssi
    
  • 1xdn – LigR 1 editing – Trypanosoma brucei
    
  • 1iuh – LigR 2’-5’ – Thermus thermophilus
    
  • 5cot – aLigR – amoeba
    
  • 6vt0, 6vt1, 6vt3, 6vt4, 6vt5, 6vtg, 5cov – aLigR (mutant)
    
• RNA ligase complex
  • 7p3b – hLigR RtcB + GMP + Co - human
    
  • 5tt6 – T4LigR 1 + ATP
    
  • 2hvr, 2hvs – T4LigR 2 + DNA + nucleotide
    
  • 2hvq - T4LigR 2 + adenosine derivative
    
  • 4qak - LigR 2’-5’ + AMP – Escherichia coli
    
  • 5cou, 6vt6, 6vt8, 6vt9, 6vtb, 6vtd – aLigR (mutant) + ATP
    
  • 6vte – aLigR (mutant) + AMP
    
  • 6vtf – aLigR + pyrophosphate
    
  • 5d1o, 5d1p – LigR ATP-dependent + ATP – Methanothermobacter thermautotrophicus
    
  • 4isz, 8dc9, 8dca, 8dcb, 8dcd, 8dcf – PhLigR RtcB + GTP + ion
    
  • 4dwq, 4it0 – PhLigR RtcB + GMP + Mn
    
  • 4isj, 4dwr – PhLigR RtcB + Mn
    
  • 7lfq – PhLigR RtcB + DNA