Structural highlights
5ie3 is a 2 chain structure with sequence from Arath. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | , |
| Related: | 5ie2, 5ie0 |
| Gene: | AAE3, 4CLL10, AMPBP3, At3g48990, T2J13.170 (ARATH) |
| Activity: | Oxalate--CoA ligase, with EC number 6.2.1.8 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
[4CLLA_ARATH] Oxalyl-CoA synthetase acting exclusively against oxalate. No activity with malonate, succinate, malate, acetate, formate, lactate, glycolate, glyoxylate or glutarate. Required for oxalate degradation, normal seed development and defense against oxalate-producing fungal pathogens.[1]
References
- ↑ Foster J, Kim HU, Nakata PA, Browse J. A previously unknown oxalyl-CoA synthetase is important for oxalate catabolism in Arabidopsis. Plant Cell. 2012 Mar;24(3):1217-29. doi: 10.1105/tpc.112.096032. Epub 2012 Mar, 23. PMID:22447686 doi:http://dx.doi.org/10.1105/tpc.112.096032