5ie3

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Crystal structure of a plant enzymeCrystal structure of a plant enzyme

Structural highlights

5ie3 is a 2 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.9Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

4CLLA_ARATH Oxalyl-CoA synthetase acting exclusively against oxalate. No activity with malonate, succinate, malate, acetate, formate, lactate, glycolate, glyoxylate or glutarate. Required for oxalate degradation, normal seed development and defense against oxalate-producing fungal pathogens.[1]

References

  1. Foster J, Kim HU, Nakata PA, Browse J. A previously unknown oxalyl-CoA synthetase is important for oxalate catabolism in Arabidopsis. Plant Cell. 2012 Mar;24(3):1217-29. doi: 10.1105/tpc.112.096032. Epub 2012 Mar, 23. PMID:22447686 doi:http://dx.doi.org/10.1105/tpc.112.096032

5ie3, resolution 1.90Å

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OCA