TRNA methyltransferase 3D structures

3D structures of tRNA methyltransferase3D structures of tRNA methyltransferase

Updated on 10-March-2020

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• tRNA guanine 9 N1 methyltransferase
  • 4jwg – fyTrm – fission yeast
    
  • 4jwf, 4jwh – fyTrm + SAH
    
  • 4jwj – yTrm + SAH – yeast
    
• tRNA guanine 37 N1 methyltransferase
  • 3knu, 6uev – ApTrm – Anaplasma phagocytophilum
    
  • 1oy5 – AaTrm – Aquifex aeolicus
    
  • 3ief – Trm – Bartonella henselae
    
  • 1uaj – HiTrm – Haemophilus influenzae
    
  • 3ky7 – Trm – Staphylococcus aureus
    
  • 3quv, 6nvr – MaTrm – Mycobacterium abscessus
    
  • 5hjj, 5yac – PabTrm – Pyrococcus abyssi
    
  • 6jki – PaTrm – Pseudomonas aeruginosa
    
  • 5zhi – MtTrm – Mycobacterium tuberculosis
    
• Complexes of tRNA guanine 37 N1 methyltransferase
  • 1uak, 4yvg – HiTrm + SAM
    
  • 1ual, 1uam – HiTrm + SAH
    
  • 3axz – HiTrm + adenosine
    
  • 4mcb, 4mcc, 4mcd – HiTrm + inhibitor
    
  • 4yvh – HiTrm + SFG
    
  • 4yvi, 4yvj, 4yvk – HiTrm + SFG + tRNA
    
  • 5d9f, 4ypw, 4ypx, 4ypy, 4ypz, 4yq0, 4yq1, 4yq2, 4yq3, 4yq4, 4yq5, 4yq6, 4yq7, 4yq8, 4yq9, 4yqa, 4yqb, 4yqc, 4yqg, 4yqi, 4yqj, 4yqk, 4yql, 4yqn, 4yqo, 4yqp, 4yqq, 4yqr, 4yqs, 4yqt, 4yqd – HiTrm + SAM competitive
    
  • 2yx1 – MjTrm + SFG – Methanocalcococcus jannaschii
    
  • 3ay0 – MjTrm + adenosine
    
  • 4h3y, 4h3z – Trm + SAH – Burkholderia phymatum
    
  • 4ig6 – ApTrm + SAH
    
  • 1p9p – EcTrm + SAH – Escherichia coli
    
  • 4gek, 4iwn – EcTrm + SAM derivative
    
  • 5hr7 – EcTrm + tRNA-Glu
    
  • 5hji, 5hjm – PabTrm + adenosine derivative
    
  • 5hjk – PabTrm + SAH
    
  • 6qo2, 6qo3, 6qo4, 6qo6, 6qoa, 6qoc, 6qod, 6qoe, 6qof, 6qog, 6qoh, 6qoi, 6qoj, 6qok, 6qol, 6qom, 6qon, 6qoo, 6qop, 6qoq, 6qor, 6qos, 6qot, 6qou, 6qov, 6qow, 6qox, 6qqq, 6qqr, 6qqt, 6qqu, 6qqv, 6qqw, 6qqz, 6qr0, 6qr1, 6qr2, 6qr3, 6qr4, 6qr7, 6qr9, 6qra, 6qrc, 6qrd, 6qre, 6qrf, 6qrg – MaTrm + inhibitor
    
  • 6nw6 – MaTrm + SAM
    
  • 6nw7 – MaTrm + SAH
    
  • 6joe, 6jof, 5zhm, 5zhn, 6afk – PaTrm + inhibitor
    
  • 6wyq – PaTrm + SAM
    
  • 6wyr – PaTrm + SFG
    
  • 5zhj – MtTrm + SAH
    
  • 5zhk, 5zhl – MtTrm + inhibitor
    
  • 5wt1 – PabTrm + tRNA + SAH
    
  • 5wt3 – PabTrm + tRNA + methylthioadenosine
    
• tRNA guanine 46 N7 methyltransferase
  • 2vdu, 2vdv – yTrm
    
  • 1yzh – Trm – Streptococcus pneumoniae
    
  • 2fca – BsTrm – Bacillus subtilis
    
  • 3dxx – EcTrm
    
• Complexes of tRNA guanine 46 N7 methyltransferase
  • 3ckk – hTrm + SAM - human
    
  • 3dxy – EcTrm + SAM
    
  • 3dxz – EcTrm + SAH
    
• Trm to O2 of cytidine 32
  • 4cnd – EcTrm (mutant)
    
  • 4xbo – EcTrm + SAH
    
  • 4cne – EcTrm (mutant) + SAH
    
• tRNA cytidine 34 O2 methyltransferase
  • 6jp6 – yTrm
    
  • 3e5y – BpTrm – Burkholderia pseudomalllei
    
  • 4jak, 4kdz – EcTrm
    
  • 6qkv – PaTrm
    
  • 6ahw – HiTrm
    
• Complexes of tRNA cytidine 34 O2 methyltransferase
  • 6jpl – yTrm + SAM
    
  • 4kgn – BpTrm + SAH
    
  • 3n4k, 3n4j – Trm + SAH – Yersinia pestis
    
  • 1mxi, 1im8 – HiTrm + SAH
    
  • 4jal – EcTrm + SAH
    

Trm to C5 of cytidine 38

• • 6fdf – fyTrm + SAH
    

Trm to O2 of cytidine/uridine

• • 5gra – Trm – Zymomonas mobilis
    
  • 5gmc, 5gmb – PaTrm
  • 5gm8 – PaTrm + SFG
    
• tRNA guanine 6 N2 methyltransferase
  • 3tm5 – PfTrm + SFG – Pyrococcvus furiosus
    
  • 3tlj – PfTrm + SAH
    
  • 3tm4 – PfTrm + SAM
    
• Trm M2G/M22G10
  • 5e71 – TkTrm – Thermococcvus kodakarensis
    
  • 5e72 – TkTrm + SAM
    
• Trm to N1 of adenine 9
  • 5a7t, 5a7z – SaTrm – Sulfolobus acidocaldarius
    
  • 4cnf – SaTrm (mutant)
    
  • 5a7y – SaTrm + SAH
    
  • 4cng – SaTrm (mutant) + SAH
    
• Trm to N1 of adenine 22
  • 6q56 – BsTrm (mutant)
    
  • 6qe6 – BsTrm + SAH
    
• tRNA adenine 58 N1 methyltransferase
  • 5ccb, 5cd1 – hTrm + SAH + tRNA-Lys
    
  • 5ccx – hTrm + tRNA-Lys
    
  • 5eqj – yTrm
    
  • 5erg – yTrm + SAM
    
  • 2pwy – TtTrm – Thermus thermophilus
    
  • 5c0o, 5c1i – TtTrm (mutant) + SAM
    
• Trm to uracil 34
  • 4qnx – EcTrm
    
  • 4qnu, 4qnv – EcTrm + SAM derivative
    
• tRNA uracil 54 methyltransferase
  • 3bt7 – yTrm + RNA
    
• Trm9-TRM112
  • 5cm2 – Trm – Yarrowia lipolytica
    
• Trm dual specificity
  • 4pl1, 4pl2 – EcTrm (mutant) + SAM
    
  • 6ems, 6emt – TkTrm
    
  • 6emu – TkTrm + SAM
    
  • 6emv –TkTrm + SAH