Crystal structure of a UMP/dUMP methylase PolB from Streptomyces cacaoi bound with 5-Br UMPCrystal structure of a UMP/dUMP methylase PolB from Streptomyces cacaoi bound with 5-Br UMP

Structural highlights

4p5a is a 4 chain structure with sequence from As 4.1602. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Gene:polB, thyX (AS 4.1602)
Activity:Thymidylate synthase (FAD), with EC number 2.1.1.148
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[C1IC19_STRCI] Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate.[HAMAP-Rule:MF_01408]

See Also

4p5a, resolution 1.76Å

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OCA