6ji6

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Crystal structure of glutathione S-transferase complexed and modified with glutathioneCrystal structure of glutathione S-transferase complexed and modified with glutathione

Structural highlights

6ji6 is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
Activity:Glutathione transferase, with EC number 2.5.1.18
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[GST26_SCHJA] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. GST isoenzymes appear to play a central role in the parasite detoxification system. Other functions are also suspected including a role in increasing the solubility of haematin in the parasite gut.

6ji6, resolution 1.50Å

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OCA