6ji6
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Crystal structure of glutathione S-transferase complexed and modified with glutathioneCrystal structure of glutathione S-transferase complexed and modified with glutathione
Structural highlights
FunctionGST26_SCHJA Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. GST isoenzymes appear to play a central role in the parasite detoxification system. Other functions are also suspected including a role in increasing the solubility of haematin in the parasite gut. See Also |
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