Atlastin

Function Atlastin (ATN) is a GTPase and a Golgi body transmembrane protein. ATN was shown to be required in membrane fusion and ER formation in Drosophila melanogaster. Disease Defects in the ATN gene are a cause of the degenerative spinal cord disorder spastic paraplegia type 3 and of hereditary sensory neuropathy type 1D. Structural highlights from human atlastin (PDB code 4ido). Water molecules shown as red spheres.

spinqualitylabelsall models Structure of human atlastin cytoplasmic domain complex with GDP and AlF4 (PDB code 4ido). Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

3D structures of atlastin3D structures of atlastin

Updated on 07-January-2019

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• Atlastin-1
  • 3q5d, 3q5e, 3qnu, 3qof – hATN cytoplasmic domain + GDP – human
    
  • 6b9d, 6b9e – hATN cytoplasmic domain (mutant) + GDP
    
  • 4idn – hATN cytoplasmic domain + GNP
    
  • 4idp – hATN cytoplasmic domain (mutant) + GNP
    
  • 4ido – hATN cytoplasmic domain + GDP + AlF4
    
  • 4idq, 6b9f – hATN cytoplasmic domain (mutant) + GDP + AlF4
    
  • 3x1d – ATN + GDP – Drosophila melanogaster
    
• Atlastin-3
  • 5vgr – hATN cytoplasmic domain + GDP