NEDD8

NEDD8 is a ubiquitin-like protein in humans. It facilitates ubiquitin conjugation. It participates in the recruitment of E2 to the ubiquitin ligase complex. NEDD8 modifies the cullin subunits (CUL) of SCF ubiquitin E3 ligase. In yeast the protein is called Rub1.

spinqualitylabelsall models Human NEDD8 complex with sulfate and Cl- (green) ions, 1ndd Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

3D Structures of NEDD83D Structures of NEDD8

Updated on 16-August-2017

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• NEDD8
  • 1ndd - hNEDD8 - human
    
  • 2ko3 – hNEDD8 – NMR
    
• NEDD8+ubiquitin-activating enzyme E1
  • 3gzn – hNEDD8+hE1 regulatory and catalytic subunits
    
  • 3dbh, 3dbl, 3dbr - hNEDD8+hE1 regulatory and catalytic subunits (mutant)
    
  • 2nvu - hNEDD8+hE1 regulatory subunit+MBP/E1 catalytic subunit+UBC12
    
  • 1r4m - hNEDD8+hE1C+amyloid beta precursor protein
    
  • 1r4n - hNEDD8+hE1C+amyloid beta precursor protein+ATP
    
• NEDD8+other proteins
  • 3dqv – hNEDD8+CUL-5
    
  • 2bkr – hNEDD8+NEDP1
    
  • 1xt9 – hNEDD8+DEN1
    
  • 4f8c – hNEDD8 + cycle inhibiting factor
    
  • 4hcp – hNEDD8 + ATP/GTP binding protein
    
  • 4fbj – hNEDD8 + bacterial effector CIF
    
  • 4p5o – hNEDD8 + cullin-1 + E3 ubiquitin-protein ligase + DCN1-like protein + UBC12
    
• Rub1
  • 1bt0 – Rub1 – Arabidopsis thaliana