UvrABC

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UvrABC endonuclease is an E. coli enzyme complex involved in DNA repair. UvrABC removes 12 nucleotides around a DNA mutation replacing them with the correct one[1]. For details on the UvrA-UvrB complex see UvrA-UvrB interaction domains.

UvrA complex with DNA, pyrophosphate and Zn+2 ion (grey) 3pih

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3D structures of UvrABC3D structures of UvrABC

Updated on 11-December-2016

ReferencesReferences

  1. Moolenaar GF, Moorman C, Goosen N. Role of the Escherichia coli nucleotide excision repair proteins in DNA replication. J Bacteriol. 2000 Oct;182(20):5706-14. PMID:11004168

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Michal Harel, Alexander Berchansky