UvrABC endonuclease is an E. coli enzyme complex involved in DNA repair. UvrABC removes 12 nucleotides around a DNA mutation replacing them with the correct one[1]. For details on the UvrA-UvrB complex see UvrA-UvrB interaction domains.
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3D structures of UvrABC3D structures of UvrABC
Updated on 11-December-2016
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- UvrA
- 3pih – TmUvrA + DNA – Thermotoga maritima
- 3zqj – UvrA – Mycobacterium tuberculosis
- 4dfc – EcUvrA + Transcription-repair-coupling factor – Escherichia coli
- 2r6f – BstUvrA – Bacillus stearothermophilus
- 3ux8 – GeUvrA - Geobacillus
- UvrB
- 1d2m, 1c4o – UvrB – Thermus thermophilus
- 1d9x – BcUvrB – Bacillus caldotenax
- 1t5l – BcUvrB (mutant)
- 1qoj – EcUvrB C terminal
- 1e52 – EcUvrB C terminal - NMR
- 1d9z – BcUvrB + ATP
- 2fdc – BcUvrB + DNA
- 2d7d, 2nmv, 3v4r – BsUvrB + DNA – Bacillus subtilis
- UvrC
- 1kft – EcUvrC C terminal
- 2nrr, 2nrt, 2nrv, 2nrw, 2nrx, 2nrz – TmUvrC C terminal
- 1ycz, 1yd0, 1yd1 – TmUvrC N terminal
- 1yd2, 1yd3, 1yd4, 1yd5 – TmUvrC N terminal (mutant)
- 1yd6 – BcUvrC N terminal
- 3c65 – BstUvrC
- UvrA-UvrB
- 3fpn – BstUvrA + UvrB
- 3uwx – GeUvrA + UvrB
ReferencesReferences
- ↑ Moolenaar GF, Moorman C, Goosen N. Role of the Escherichia coli nucleotide excision repair proteins in DNA replication. J Bacteriol. 2000 Oct;182(20):5706-14. PMID:11004168
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