HCMV DNA polymerase processivity subunit UL44 at neutral pH and low saltHCMV DNA polymerase processivity subunit UL44 at neutral pH and low salt

Structural highlights

5ixa is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[VPAP_HCMVA] Accessory subunit of the DNA polymerase that acts to increase the processivity of polymerization.[1]

References

  1. Kim YE, Ahn JH. Role of the specific interaction of UL112-113 p84 with UL44 DNA polymerase processivity factor in promoting DNA replication of human cytomegalovirus. J Virol. 2010 Sep;84(17):8409-21. doi: 10.1128/JVI.00189-10. Epub 2010 Jun 10. PMID:20538862 doi:http://dx.doi.org/10.1128/JVI.00189-10

5ixa, resolution 2.68Å

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OCA