Proteopedia

1t6l

Crystal Structure of the Human Cytomegalovirus DNA Polymerase Subunit, UL44Crystal Structure of the Human Cytomegalovirus DNA Polymerase Subunit, UL44

Structural highlights

1t6l is a 1 chain structure with sequence from Human betaherpesvirus 5. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.85Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

VPAP_HCMVA Accessory subunit of the DNA polymerase that acts to increase the processivity of polymerization.[1]

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Kim YE, Ahn JH. Role of the specific interaction of UL112-113 p84 with UL44 DNA polymerase processivity factor in promoting DNA replication of human cytomegalovirus. J Virol. 2010 Sep;84(17):8409-21. doi: 10.1128/JVI.00189-10. Epub 2010 Jun 10. PMID:20538862 doi:http://dx.doi.org/10.1128/JVI.00189-10

1t6l, resolution 1.85Å

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OCA
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