Transferrin
FunctionFunction
Transferrin or serotransferrin (TF) is an iron-binding protein. TF delivers iron from absorption centers in the duodendum and white blood cell macrophages to all tissues[1]. TF contains two lobes: at the N and C termini. Ovotransferrin (OTF) is a glycosylated TF of egg white. For details see Molecular Playground/Transferrin.
RelevanceRelevance
Carbohydrate-deficient TF may help diagnose alcoholic liver disease[2].
3D Structures of Transferrin3D Structures of Transferrin
Updated on 21-September-2016
ReferencesReferences
- ↑ de Jong G, van Dijk JP, van Eijk HG. The biology of transferrin. Clin Chim Acta. 1990 Sep;190(1-2):1-46. PMID:2208733
- ↑ Liu YS, Xu GY, Cheng DQ, Li YM. Determination of serum carbohydrate-deficient transferrin in the diagnosis of alcoholic liver disease. Hepatobiliary Pancreat Dis Int. 2005 May;4(2):265-8. PMID:15908327