Crystal structure of apo-PEPCK from Mycobacterium tuberculosis with glycerolCrystal structure of apo-PEPCK from Mycobacterium tuberculosis with glycerol

Structural highlights

4wie is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Activity:Phosphoenolpyruvate carboxykinase (GTP), with EC number 4.1.1.32
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[PCKG_MYCTA] Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.

See Also

4wie, resolution 2.18Å

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OCA