Crystal Structure of E83A mutant of Mtb PEPCK in complex with PEP and GDPCrystal Structure of E83A mutant of Mtb PEPCK in complex with PEP and GDP

Structural highlights

4wpu is a 1 chain structure with sequence from Mycobacterium tuberculosis H37Ra. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.26Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PCKG_MYCTA Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.

See Also

4wpu, resolution 2.26Å

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