Pertussis toxin

Template:STRUCTURE 1prt

Pertussis toxin (PT) is produced by the bacterium Bordetella pertussis and is the cause of whooping cough^[1]. For additional details see Pertussis Toxin-ATP Complex.
Pertactin is another toxin produced by Bordetella. For details see P.69 Pertactin Structure and Function.

3D Structures of Pertussis toxin3D Structures of Pertussis toxin

1prt – BpPT - Bordetella pertussis
1pto – BpPT + galactose
1bcp – BpPT + ATP

Pertactin

1dab - BpPer
2iou - Per extracellular domain + major tropism determinant - Bordetella bronchiseptica

ReferencesReferences

↑ Carbonetti NH, Artamonova GV, Andreasen C, Bushar N. Pertussis toxin and adenylate cyclase toxin provide a one-two punch for establishment of Bordetella pertussis infection of the respiratory tract. Infect Immun. 2005 May;73(5):2698-703. PMID:15845471 doi:http://dx.doi.org/10.1128/IAI.73.5.2698-2703.2005

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Jonathan Tringali, Michal Harel

[1] Carbonetti NH, Artamonova GV, Andreasen C, Bushar N. Pertussis toxin and adenylate cyclase toxin provide a one-two punch for establishment of Bordetella pertussis infection of the respiratory tract. Infect Immun. 2005 May;73(5):2698-703. PMID:15845471 doi:http://dx.doi.org/10.1128/IAI.73.5.2698-2703.2005

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