CD2
<StructureSection load='1hnf' size='450' side='right' caption='Structure of glycosylated human CD2 extracellular domain complex with Na+ ion (PDB entry 1hnf)' scene='55/551235/Cv/1'>
CD2 (or Cluster of Differentiation 2) is a cell adhesion molecule found on the surface of T-cells and Natural Killer cells. CD2 has 2 immunoglobulin-like (Ig) domains in its extracellular portion.[1]
3D structures of CD23D structures of CD2
Updated on 29-November-2015
1cdb, 1gya – hCD2 adhesion domain – human - NMR
1hnf – hCD2 extracellular domain
1qa9 – hCD2 N terminal domain (mutant) + CD58 adhesion domain (mutant)
1hng – rCD2 extracellular domain - rat
1cdc – rCD2 N terminal domain
1a64, 1a6p, 1a7b – rCD2 adhesion domain (mutant)
1cld – CD2 (mutant) – Kluyveromyces lactis – NMR
ReferencesReferences
- ↑ Wilkins AL, Yang W, Yang JJ. Structural biology of the cell adhesion protein CD2: from molecular recognition to protein folding and design. Curr Protein Pept Sci. 2003 Oct;4(5):367-73. PMID:14529530
- ↑ Bodian DL, Jones EY, Harlos K, Stuart DI, Davis SJ. Crystal structure of the extracellular region of the human cell adhesion molecule CD2 at 2.5 A resolution. Structure. 1994 Aug 15;2(8):755-66. PMID:7994575