Template:STRUCTURE 3mfr
Ca2+/Calmodulin dependent protein kinase (CaMK) phosphorylates Ser and Thr. It is regulated by Ca2+/Calmodulin (CaM). It contains an N-terminal catalytic domain, regulatory domain (CBD) and association domain (ASD). CaMKI is a specialized CaM kinase while CaMKII is multifunctional kinase. CASK is a membrane associated CaMK. DAPK is a death-associated CaMK which protects cells from some programmed cell death. It contains a regulatory (RD) and autoinhibitory (AD) domains.
3D Structures of Ca2+/Calmodulin dependent protein kinase3D Structures of Ca2+/Calmodulin dependent protein kinase
Updated on 15-November-2015
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- CaMKK – CaM kinase kinase
- 1iq5 – CeCaMK CBD+XlCaM – Xenopus laevis
- CaMKI – specialized CaM kinase
- 1mxe – rCaMKI CBD+CaM – rat
- 1ckk – rCaMK CBD chain B+XlCaM
- 1a06 – rCaMK chain A
- CASK – membrane-associated CaMK
- 3mfr – hCASK CBD – human
- 3mfs – hCASK+AMPPNP
- 3mft – hCASK+Mn
- 3c0g – hCASK kinase domain
- 3c0h - hCASK kinase domain+AMPPNP
- 3c0i - hCASK kinase domain+AMP
- 3mfu - hCASK+AMPPNP+Mn
- DAPK – death-associated CaMK
- 2x0g – hDAPK RD+AD+CaM
- 2cke – hDAPK+inhibitor
- CaMKII – multifunctional CaM kinase
- 2vz6 - hCaMKII α chains A, B+ indirubin-E804
- 2zv2 – hCaMKII+STO-609
- 2wel - hCaMKII δ chain D+CaM
- 2w2c - hCaMKII δ chain ASD
- 2vn9 - hCaMKII δ chains A-B
- 3bhh - hCaMKII β chains A-D
- 2v7o - hCaMKII γ chain A
- 2ux0 - hCaMKII γ (mutant) chains A-F
- 2jam - hCaMKI γ+peptides
- 2jc6 - hCaMKII δ chains A,C
- 1hkx - mCaMKII α chains A-N ASD - mouse
- 3gp2 – cCaMKII δ chain B+CaM – chicken
- 3kk8, 3kk9 – CeCaMKII – Caenorhabditis elegans
- 3kl8 – CeCaMKII (mutant)+inhibitor
- 3ksp – CaMKII ASD – Exiguobacterium sibiricum
- CaMKIV
See alsoSee also
Calcium-dependent protein kinase, a member of the CaM kinase family