Atlastin

<StructureSection load='4ido' size='340' side='right' caption='Structure of human atlastin cytoplasmic domain complex with GDP and AlF4 (PDB code 4ido).' scene=>

FunctionFunction

Atlastin (ATN) is a GTPase and a Golgi body transmembrane protein. ATN was shown to be required in membrane fusion and ER formation in Drosophila melanogaster.

DiseaseDisease

Defects in the ATN gene are a cause of the degenerative spinal cord disorder spastic paraplegia type 3.

3D structures of atlastin3D structures of atlastin

Updated on 08-November-2015

3q5d, 3q5e, 3qnu, 3qof – hATN cytoplasmic domain + GDP – human
4idn – hATN cytoplasmic domain + GNP
4idp – hATN cytoplasmic domain (mutant) + GNP
4ido – hATN cytoplasmic domain + GDP + AlF4
4idq – hATN cytoplasmic domain (mutant) + GDP + AlF4