5e26

Crystal structure of human PANK2: the catalytic core domain in complex with pantothenate and adenosine diphosphateCrystal structure of human PANK2: the catalytic core domain in complex with pantothenate and adenosine diphosphate

Structural highlights

5e26 is a 4 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:	, , , ,
Activity:	Pantothenate kinase, with EC number 2.7.1.33
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum

Disease

[PANK2_HUMAN] Atypical pantothenate kinase-associated neurodegeneration;Classic pantothenate kinase-associated neurodegeneration. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.

Function

[PANK2_HUMAN] May be the master regulator of the CoA biosynthesis.

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OCA