Crystal structure of human PANK2: the catalytic core domain in complex with pantothenate and adenosine diphosphateCrystal structure of human PANK2: the catalytic core domain in complex with pantothenate and adenosine diphosphate

Structural highlights

5e26 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.14Å
Ligands:, , , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Disease

PANK2_HUMAN Atypical pantothenate kinase-associated neurodegeneration;Classic pantothenate kinase-associated neurodegeneration. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.

Function

PANK2_HUMAN May be the master regulator of the CoA biosynthesis.

See Also

5e26, resolution 2.14Å

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