Annexin

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Template:STRUCTURE 1ain

Annexins are proteins which make a membrane scaffold. They bind negatively charged phospholipids and contain a 70 amino acid long annexin repeat. They consist of 2 domains - the C-terminal core and the N-terminal head. Annexins divide into species and are numbered from I to XII. Annexin V is the most abundant scaffolding protein. Annexin E1 (AnE1) is associated with tubulin in trophozoites of Giardia lamblia and forms local slubs in the flagella. In the annexin image calcium ions are shown as green balls.

3D structures of annexin3D structures of annexin

Updated on 01-February-2015

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Alexander Berchansky, Michal Harel, Jaime Prilusky