Serpin

Serpin or serine protease inhibitor (Ser) are protease inhibitors. Ser E1 is antithrombin. Ser C1 is antithrombin. Ser A5 is protein C inhibitor. Ser A6 is a cortisol-binding globulin. Ser A8 is angiotensinogen. Ser A7 is a thyroxine-binding globulin. Ser B1 is leukocyte elastase inhibitor. Ser B3 is squamos cell carcinoma antigen 1. Ser B5 is Maspin. Ser I1 is neuroserpin. Ser A10 is protein Z-related protease inhibitor. Ser A1 is alpha-1 antitrypsin. Ser A3 is α 1-antichymotrypsin. Ser E1 is plasminogen activator inhibitor 1.

spinqualitylabelsall models Structure of cleaved human serpin A1. Residues 46-382 (grey), residues 383-418 (green). (PDB entry 3ndd) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

3D structures of serpin3D structures of serpin

Updated on 10-December-2014

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• Serpin
  • 1mtp, 1sng – Ser – Thermobifida fusca
• Serpin A1 see Alpha-1-antitrypsin
• Serpin A3 (α 1-antichymotrypsin)
  • 2ach, 1as4, 3caa – hSer-A3
    
  • 4caa, 1qmn, 3dlw – hSer-A3 (mutant)
    
  • 1yxa – Ser-A3N - mouse
    
• Serpin A5
  • 2ol2 – hSer-A5
    
  • 3dy0 – hSer-A5 + heparin
• Serpin A6 see Corticosteroid-binding globulin
• Serpin A7
  • 2riv – hSer-A7
    
  • 2riw – hSer-A7 + thyroxine
    
  • 2xn3 – hSer-A7 + mefenamic acid
    
  • 2xn5 – hSer-A7 + furosemide
    
  • 2xn6, 2xn7 – hSer-A7 + thyroxine-fluoresein
• Serpin A8
  • 2jp8 – hSer-A8 – NMR
    
  • 2wxw – hSer-A8
    
  • 2x0b – hSer-A8 + renin
    
  • 2wxx, 2wxy, 2wy0 – Ser-A8 – mouse
    
  • 2wxz, 2wy1 – rSer-A8
• Serpin A10
  • 3h5c, 3f1s – hSer-A10 + vitamin K-dependent protein Z
• Serpin A12
  • 4if8 – hSer-A12
    
• Serpin B1 (leukocyte elastase inhibitor)
  • 1hle – Ser-B1 – horse
    
  • 4ga7 – hSer-B1 (mutant)
    
• Serpin B3
  • 2zv6 – hSer-B3
• Serpin B5 (Maspin)
  • 1xqg, 1wz9, 1xu8 - hSer-B5
    
  • 1xqj – hSer-B5 (mutant)
    
• Serpin C1 see Antithrombin
• Serpin E1 see Plasminogen activator inhibitor
• Serpin E2
  • 4dy0 – hSer-E2 + heparin
• Serpin-I1
  • 3fgq, 2f02, 3f5n – hSer-I1
• Serpin K
  • 1sek – ThSer-K – Tobacco hornworm
• Serpin 1
  • 1k9o – ThSer-1 (mutant) + trypsin II
    
  • 3le2 – Ser-1 – Arabidopsis thaliana
• Serpin 2
  • 1m93 – Ser-2 – Cowpox virus
    
  • 3nda – Ser-2 – Sheep tick
    
  • 3pzf – Ser-2 – malaria mosquito