The crystallographic structure of Aldose Reductase IDD393 complex confirms Leu300 as a specificity determinantThe crystallographic structure of Aldose Reductase IDD393 complex confirms Leu300 as a specificity determinant

Structural highlights

2pzn is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Related:1us0
Gene:ALDR1 (Homo sapiens)
Activity:Aldehyde reductase, with EC number 1.1.1.21
Resources:FirstGlance, OCA, RCSB, PDBsum

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2pzn, resolution 1.00Å

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OCA