2pzn

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The crystallographic structure of Aldose Reductase IDD393 complex confirms Leu300 as a specificity determinantThe crystallographic structure of Aldose Reductase IDD393 complex confirms Leu300 as a specificity determinant

Structural highlights

2pzn is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ALDR_HUMAN Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2pzn, resolution 1.00Å

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OCA