Trehalulose synthase

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<StructureSection load='2pwe' size='340' side='right' caption='Structure of trehalulose synthase complex with sucrose (stick model) and Ca+2 ion (green) (PDB code 2pwe).' scene=>

FunctionFunction

Trehalulose synthase (THS) converts sucrose to trehalulose (TH).

DiseaseDisease

RelevanceRelevance

Since TH is a sugar substitute and is absorbed more slowly than sucrose it can be used in diabetic and sports food and drinks.

Structural highlightsStructural highlights

3D structures of trehalulose synthase3D structures of trehalulose synthase

Updated on 21-August-2014

Trehalulose synthaseTrehalulose synthase

1zja, 1zjb, 2pwh – PmTHS – Pseudomonas mesoacidophila
4go9, 4go8 – PmTHS (mutant)
4h2c, 4h8h – RhTHS (mutant) - Rhizobium

Trehalulose synthase complexTrehalulose synthase complex

2pwd, 2pwg – PmTHS + inhibitor
2pwe – PmTHS (mutant) + sucrose
2pwf – PmTHS (mutant) + glucose
4gi6, 4h7v – RhTHS (mutant) + glucose
4gi8 – RhTHS (mutant) + sucrose
4h8v – RhTHS + TH
4gi9 – RhTHS (mutant) + TH
4h8u – RhTHS (mutant) + sucrose + TH
4gia, 4ha1 – RhTHS (mutant) + isomaltulose
4gin – RhTHS (mutant) + inhibitor


ReferencesReferences

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky