Trehalulose synthase

Function Trehalulose synthase or sucrose isomerase (THS) converts sucrose to trehalulose (TH). Relevance Since TH is a sugar substitute and is absorbed more slowly than sucrose it can be used in diabetic and sports food and drinks. Structural highlights (water molecules are shown as red spheres) in a with mostly conserved residues.

spinqualitylabelsall models Structure of trehalulose synthase complex with sucrose and Ca+2 ion (green) (PDB code 2pwe). Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

3D structures of trehalulose synthase3D structures of trehalulose synthase

Updated on 16-December-2020

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• Trehalulose synthase
  • 1zja, 1zjb, 2pwh – PmTHS – Pseudomonas mesoacidophila
    
  • 4go9, 4go8 – PmTHS (mutant)
    
  • 4h2c, 4h8h – RhTHS (mutant) - Rhizobium
    
  • 3gbd – PrTHS – Protaminobacter rubrum
    
  • 4how – ErTHS – Erwinia rhapontici
    
• Trehalulose synthase complex
  • 2pwd, 2pwg – PmTHS + inhibitor
    
  • 2pwe – PmTHS (mutant) + sucrose
    
  • 2pwf – PmTHS (mutant) + glucose
    
  • 4hoz – ErTHS + glucose
    
  • 4hph – ErTHS + sucrose
    
  • 4gi6, 4h7v – RhTHS (mutant) + glucose
    
  • 4gi8 – RhTHS (mutant) + sucrose
    
  • 4h8v – RhTHS + TH
    
  • 4gi9 – RhTHS (mutant) + TH
    
  • 4h8u – RhTHS (mutant) + sucrose + TH
    
  • 4gia, 4ha1 – RhTHS (mutant) + isomaltulose
    
  • 4gin – RhTHS (mutant) + inhibitor
    
  • 3gbe – PrTHS + inhibitor