4omt

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Crystallization and preliminary crystallographic analysis of human muscle phosphofructokinase, the main regulator of glycolysisCrystallization and preliminary crystallographic analysis of human muscle phosphofructokinase, the main regulator of glycolysis

Structural highlights

4omt is a 1 chain structure. Full crystallographic information is available from OCA.
Related:3o8n, 3opy
Activity:Glucokinase, with EC number 2.7.1.2
Resources:FirstGlance, OCA, RCSB, PDBsum

Disease

[K6PF_HUMAN] Glycogen storage disease due to muscle phosphofructokinase deficiency. The disease is caused by mutations affecting the gene represented in this entry.

Function

[K6PF_HUMAN] Catalyzes the third step of glycolysis, the phosphorylation of fructose-6-phosphate (F6P) by ATP to generate fructose-1,6-bisphosphate (FBP) and ADP.[HAMAP-Rule:MF_00339]

4omt, resolution 6.00Å

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OCA