Crystal structure of Pichia pastoris phosphofructokinase in the T-stateCrystal structure of Pichia pastoris phosphofructokinase in the T-state
Structural highlights
3opy is a 12 chain structure with sequence from Komagataella pastoris DSMZ 70382. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
PFKA1_PICPA Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.[HAMAP-Rule:MF_03184][1]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
↑Kirchberger J, Bar J, Schellenberger W, Dihazi H, Kopperschlager G. 6-phosphofructokinase from Pichia pastoris: purification, kinetic and molecular characterization of the enzyme. Yeast. 2002 Aug;19(11):933-47. PMID:12125050 doi:http://dx.doi.org/10.1002/yea.885