Sandbox Reserved 818

This Sandbox is Reserved from 06/12/2018, through 30/06/2019 for use in the course "Structural Biology" taught by Bruno Kieffer at the University of Strasbourg, ESBS. This reservation includes Sandbox Reserved 1480 through Sandbox Reserved 1543.

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Template:STRUCTURE 1prt

File:1prt.png

PERTUSSIS TOXINPERTUSSIS TOXIN

About this StructureAbout this Structure

1prt is a 12 chain structure with sequence from Bordetella pertussis. The September 2005 RCSB PDB Molecule of the Month feature on Cholera Toxin by David S. Goodsell is 10.2210/rcsb_pdb/mom_2005_9. Full crystallographic information is available from OCA.

IntroductionIntroduction

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Binding of PTX to its cellular targetsBinding of PTX to its cellular targets

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Toxin entry and trafficking in target cellsToxin entry and trafficking in target cells

Mechanism of PTX-catalysed ADP-ribosylationMechanism of PTX-catalysed ADP-ribosylation

Enzymatically active S1 subunit in the A protomer This subunit

Toxic effects of pertussis toxinToxic effects of pertussis toxin

ReferenceReference

^{[xtra 1]}

↑ Stein PE, Boodhoo A, Armstrong GD, Cockle SA, Klein MH, Read RJ. The crystal structure of pertussis toxin. Structure. 1994 Jan 15;2(1):45-57. PMID:8075982

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA, Lea Clusan, Paul Giroud

[1] Stein PE, Boodhoo A, Armstrong GD, Cockle SA, Klein MH, Read RJ. The crystal structure of pertussis toxin. Structure. 1994 Jan 15;2(1):45-57. PMID:8075982

[xtra 1]