CD2-associated protein
<StructureSection load='2j6f' size='350' side='right' caption='Structure of human CD2AP SH3 domain 1 complex with E3 ubiquitin ligase peptide (pink) (PDB entry 2j6f)' scene=>
CD2-associated protein (CD2AP) called also CMS, is a scaffolding protein which regulates actin cytoskeleton. CD2AP SH3 domain interacts with actin and a variety of membrane proteins. CD2AP contains in its N-terminal 3 SH3 domains followed by a proline-rich region.
3D structures of CD2-associated protein3D structures of CD2-associated protein
Updated on 26-November-2013
CD2AP SH3 domain 1CD2AP SH3 domain 1
2j6k – hCD2AP – human
2krm – mCD2AP – mouse - NMR
2j6f – hCD2AP + E3 ubiquitin protein ligase peptide
2j6o, 2j7i – hCD2AP + CD2 peptide
CD2AP SH3 domain 2CD2AP SH3 domain 2
2fei – hCD2AP – NMR
2krn – mCD2AP– NMR
3u23 - hCD2AP + RIN3 proline-rich peptide
CD2AP SH3 domain 3CD2AP SH3 domain 3
2jte, 2kro – mCD2AP - NMR
2lz6 – hCD2AP + ubiquitin - NMR