Death-associated protein

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Death-associated protein (DAP) is associated with multiple cellular functions. DAP6 or DAXX interacts with apoptosis antigen. It has both pro- and anti-apoptosis functions. DAP5 is an inhibitor of translational initiation in differentiation and apoptosis. For more details on DAP5 see Death Associated Protein 5.

3D structures of death-associated protein

Death-associated protein 5

3d3m - hDAP C terminal

Death-associated protein 6

2kzs - hDAXX helical bundle domain – NMR

2kzu - hDAXX helical bundle domain + RASSF1C - NMR


Structure of two monomers of human death-associated protein 5 C terminal (PDB entry 3d3m)

Drag the structure with the mouse to rotate

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Michal Harel, Alexander Berchansky