Death-associated protein


Death-associated protein (DAP) or death domain-associated protein is associated with multiple cellular functions.

  • DAP6 or Daxx interacts with apoptosis antigen. It has both pro- and anti-apoptosis functions.[1]
  • DAP5 is an inhibitor of translational initiation in differentiation and apoptosis. For more details on DAP5 see Death Associated Protein 5.

3D structures of death-associated protein

Death-associated protein 3D structures


Structure of human death-associated protein 5 C terminal (PDB entry 3d3m)

Drag the structure with the mouse to rotate

ReferencesReferences

  1. Yang X, Khosravi-Far R, Chang HY, Baltimore D. Daxx, a novel Fas-binding protein that activates JNK and apoptosis. Cell. 1997 Jun 27;89(7):1067-76. PMID:9215629

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky