2bdf

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Template:STRUCTURE 2bdf

File:2bdf.png

Src kinase in complex with inhibitor AP23451Src kinase in complex with inhibitor AP23451

Template:ABSTRACT PUBMED 16492148

About this StructureAbout this Structure

2bdf is a 2 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. Dalgarno D, Stehle T, Narula S, Schelling P, van Schravendijk MR, Adams S, Andrade L, Keats J, Ram M, Jin L, Grossman T, MacNeil I, Metcalf C 3rd, Shakespeare W, Wang Y, Keenan T, Sundaramoorthi R, Bohacek R, Weigele M, Sawyer T. Structural basis of Src tyrosine kinase inhibition with a new class of potent and selective trisubstituted purine-based compounds. Chem Biol Drug Des. 2006 Jan;67(1):46-57. PMID:16492148 doi:10.1111/j.1747-0285.2005.00316.x

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