Stromal Derived Factor 1

NMR Structure of the Stromal Derived Factor 1α, 2kec

Stromal Derived Factor 1 (SDF-1α) or CXCL12 is a small cytokine from the chemokine family. It is natural ligand of CXCR4 It has a role in angiogenesis, tumor metastasis and the migration of cells from the liver to the bone marrow during embryogenesis. The images on the left and right correspond to one representative SDF-1α structure, i.e. the human SDF-1α (2kec).

3D Structures of Stromal Derived Factor 13D Structures of Stromal Derived Factor 1

2kec, 2ked, 2kee, 2sdf, 1sdf - hSDF1α – NMR - human
2k0l, 2k01 – hSDF1α (mutant) – NMR
1a15 - hSDF1α (mutant)
2nwg - hSDF1α+heparin
2j7z - hSDF1α residues 22-89
2k03, 2k04, 2k05 - hSDF1α (mutant)+ hCXCR4 N-terminal (mutant)