Crystal structure of Mus musculus iodotyrosine deiodinase (IYD) C217A, C239A bound to FMNCrystal structure of Mus musculus iodotyrosine deiodinase (IYD) C217A, C239A bound to FMN

Structural highlights

3to0 is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.655Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

IYD1_MOUSE Catalyzes the oxidative NADPH-dependent deiodination of monoiodotyrosine (L-MIT) or diiodotyrosine (L-DIT). Acts during the hydrolysis of thyroglobulin to liberate iodide, which can then reenter the hormone-producing pathways. Acts more efficiently on monoiodotyrosine than on diiodotyrosine (By similarity).

See Also

3to0, resolution 2.66Å

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