Crystal structure of UBA2ufd-Ubc9: insights into E1-E2 interactions in Sumo pathwaysCrystal structure of UBA2ufd-Ubc9: insights into E1-E2 interactions in Sumo pathways

Structural highlights

3ong is a 4 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.3Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

UBA2_YEAST The dimeric enzyme acts as a SMT3 E1 ligase. It mediates ATP-dependent activation of SMT3 and formation of a thioester with a conserved cysteine residue on AOS1.

See Also

3ong, resolution 2.30Å

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