Crystal Structure of AaV-SP-II, a Glycosylated Snake Venom Serine Proteinase from Agkistrodon acutusCrystal Structure of AaV-SP-II, a Glycosylated Snake Venom Serine Proteinase from Agkistrodon acutus

Structural highlights

1op2 is a 1 chain structure with sequence from Deinagkistrodon acutus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.1Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

VSPP_DEIAC Snake venom serine protease that has fibrinogenolytic activities. Also possess esterolysis and amidolytic activities.[1] [2]

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. Zhu Z, Gong P, Teng M, Niu L. Purification, N-terminal sequencing, partial characterization, crystallization and preliminary crystallographic analysis of two glycosylated serine proteinases from Agkistrodon acutus venom. Acta Crystallogr D Biol Crystallogr. 2003 Mar;59(Pt 3):547-50. Epub 2003, Feb 21. PMID:12595722
  2. Zhu Z, Liang Z, Zhang T, Zhu Z, Xu W, Teng M, Niu L. Crystal structures and amidolytic activities of two glycosylated snake venom serine proteinases. J Biol Chem. 2005 Mar 18;280(11):10524-9. Epub 2005 Jan 4. PMID:15632114 doi:10.1074/jbc.M412900200

1op2, resolution 2.10Å

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