Proteinase 3D structures

3D structures of proteinase3D structures of proteinase

Updated on 17-December-2023

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• Proteinase A or saccharopepsin
  • 2jxr, 1fmu, 1fmx – yPRO - yeast
    
  • 1dp5, 1dpj, 1g0v - yPRO + polypeptide inhibitor IA3
    
  • 1fq5, 1fq6, 1fq7, 1fq8 - yPRO + inhibitor
    
  • 2sga – SgPRO – Streptomyces griseus
    
  • 1sgc - SgPRO + chymostatin A
    
  • 3sga, 4sga, 5sga - SgPRO + polypeptide inhibitor
    
  • 4fvd – hevPRO 2A + peptide – human enterovirus
    
  • 4fvb – hevPRO 2A (mutant)
    
• Proteinase B
  • 1cso, 1ct0, 1ct2, 1ct4, 1ds2, 1sgd, 1sge, 1sgn, 1sgp, 1sgq, 1sgr, 1sgy, 2nu3, 2nu4, 2sgd, 2sge, 2sgp, 2sgq, 2sgf, 3sgb, 3sgq – SgPRO + turkey ovomucoid inhibitor>נר .<
  • 4sgb - SgPRO + potato inhibitor
• Proteinase K
  • 2prk, 1cnm, 1egq, 2id8, 2g4v, 2v8b, 3gt3, 3gt4, 3d9q, 3ddz, 3de0, 3de1, 3de2, 3de3, 3de4, 3de5, 3de6, 3de7, 3dvq, 3dvr, 3dvs, 3dw1, 3dw3, 3dwe, 3i2y, 3i30, 3i37, 3i34, 3l1k, 3aj8, 3aj9, 3q40, 3q5g, 3qmp, 4b5l, 4fon, 6rzp, 6qf1, 6pu5, 6pu4, 6n4u, 6mh6, 6fjs, 6clb, 6cla, 6cl9, 6cl8, 6cl7, 5wjh, 5wjg, 5whw, 5uvl, 6j43, 6k2p, 6k2r, 6k2s, 6k2t, 6k2v, 6k2w, 6pq0, 6pq4, 6v8r, 7c0p, 7nuz, 7s4z, 8f05, 8f06, 8f07, 8sog, 8sqv – EaPRO + Ca – Engyodontium album
    
  • 7ln7, 7lpt, 7lpu, 7lpv, 7lq8, 7lq9, 7lqa, 7lqb, 7lqc, 7ltd, 7lti, 7ltv, 7lu0, 7lu1, 7lu2, 7lu3 - EaPRO + Ca – radiation damage
    
  • 1ic6, 6qxv – EaPRO (mutant) + Ca
    
  • 1ptk, 1ht3 – EaPRO + Ca + Hg
    
  • 2pkc, 7a68 – EaPRO + Na
    
  • 5wrc, 6k2x – EaPRO + Pr
    
  • 6txg – EaPRO + Ru
    
  • 4dj5, 4woc, 4wob, 7njj, 7nuy – EaPRO
    
  • 6clb, 6cla, 6cl9, 6cl8, 6cl7, 6pkt, 6pks, 6pkr, 6pkq, 6pkp, 6pko, 6pkn, 6pkm, 6pkl, 6pkk, 6pkj, 6law, 6zet, 6zeu, 6zevת 7skx, 7svy, 7svz, 7sw0, 7sw1, 7sw2, 7sw3, 7sw4, 7sw5, 7sw6, 7sw7, 7sw8, 7sw9, 7swa, 7swb, 7swc, 8sdk, 8e52, 8e53, 8fyo, 8fyp, 8fyq, 8fyr, 8fys – EaPRO - MicroED
    
• Proteinase K complex with peptide
  • 3prk, 1p7v, 1p7w – EaPRO + Ca + peptide inhibitor
    
  • 1bjr, 2dqk, 2duj – EaPRO + Ca + lactoferrin peptide
    
  • 2hd4 – EaPRO + Ca + lactoferrin peptide inhibitor
    
  • 2dp4, 3ptl – EaPRO + lactoferrin peptide
    
  • 1pek, 1pfg, 4zar – EaPRO + peptide inhibitor
    
  • 1pj8 – EaPRO + Hg + substrate analog peptide
    
  • 2hpz, 2pq2, 6kkfת 8sou, 8sov, 8spl – EaPRO + Ca + peptide
    
  • 3osz – EaPRO + Ca + antimicrobial peptide
    
  • 2b6n – PRO + tripeptide - Serratia
    
• Proteinase K complex with small molecule
  • 2pwb – EaPRO + Ca + coumarin
    
  • 2pyz – EaPRO + Ca + auramine
    
  • 2pwa – EaPRO + Ca + alanine boronic acid
    
  • 1oyo – EaPRO + Ca + melanin monomer
    
  • 3dyb – EaPRO + Ca + digalacturonic acid
    
  • 6rvg, 6rve, 6ruw, 6run, 6ruk, 6ruh, 6rug, 7a9f, 7a9k, 7a9m – EaPRO + keggin derivative
    
  • 6k8m – EaPRO + urea derivative
    
  • 7jsy – EaPRO + triiodoisophthalate derivative - MicroED
    
• Proteinase 3C
  • 1hav, 1qa7 – hvPRO – Hepatitis virus
    
  • 2h6m, 2h9h, 2hal – hvPRO + peptide inhibitor
    
  • 2vb0, 2zu3, 2zty, 2ztz, 3zyd - PRO – Coxsakievirus
    
  • 2zu1, 3zye – csvPRO (mutant)
    
  • 2ztx – csvPRO + inhibitor
    
  • 3zzd, 3zzc, 3zza, 3zzb, 3zz8, 3zz9, 3zz7, 3zz5, 3zz3, 3zz4 – csvPRO (mutant) + inhibitor
    
  • 4ghq – hevPRO
    
  • 4ght – hevPRO + common cold drug
    
  • 4ghq – evPRO - Enterovirus
    
  • 4ght, 5c1u, 5c1x, 5c1y, 5c20, 5dp3 5dp4, 5dp5, 5dp6, 5dp7, 5dp8, 5dp9, 5dpa, 6lka, 7dnc – evPRO + inhibitor
    
  • 5hm2 – PRO - Foot-and-mouth virus
    
  • 1l1n – PRO - polio virus
    
• PRO 3C-like see Virus protease
• Thermostable neutral proteinase see Thermolysin
• H2-Proteinase
  • 1wni – PRO – Trimeresurus flavoviridis
• Aspartic Proteinase
  • 1fq4 - yPRO + inhibitor
    
  • 2asi – PRO – Rhizomucor miehei
    
  • 1zap, 2h6s – CaPRO – Candida albicans
    
  • 1eag – CaPRO + inhibitor
    
  • 4ybf – PRO – Candida parasilosis
    
  • 1izd - AoPRO – Aspergillus oryzae
    
  • 1ize - AoPRO + polypeptide-statin inhibitor
    
  • 1j71 - PRO + polypeptide inhibitor – Candida tropicalis
    
  • 1wkr - PRO + polypeptide-statin inhibitor – Irpex lacteus
    
  • 3apr - PRO + polypeptide inhibitor – Rhizopus chinesis
    
  • 1epl, 1epm, 2er0, 2er9, 4er4 - fuPRO + polypeptide inhibitor – fungus
    
  • 1epo, 1epp, 1epq - fuPRO + intermediate
    
  • 3emy - PRO + pepstatin – Hypocrea jecorina<br />
  • 1mpp - PRO – Mucor pusillus
    
  • 3c9x - PRO – Trichoderma reesei
    
• Aspartic PRO from Plasmodium vivax see Plasmepsin
• Cysteine Proteinase or gingipain
  • 2e03, 2e02, 2e01, 2e00, 2dzz, 2dzy – yPRO 1 (mutant)
    
  • 2hrv – PRO 2A – human rhinovirus
    
  • 3m1h, 4itc – PgPRO adhesion domain residues 982-1154 – Porphyromonas gingivalis
    
  • 1cvr, 4rbm, 4tkx – PgPRO catalytic domain residues 229-683
    
  • 6i9a – PgPRO catalytic domain + inhibitor
    
  • 5mun – PgPRO residues 20-228
    
  • 2fo5 – PRO residues 133-356 + leupeptin – Hordenum vulgare
    
  • 1cv8, 1x9y – SaPRO – Staphylococcus aureus
    
  • 1y4h, 1pxv – SaPRO + PRO inhibitor
    
  • 6p4e – PRO B (mutant) – Leishmania mexicana
    
  • 1z8r – csvPRO
    
• Serine Proteinase
  • 5m3n, 1lcy – hPRO HTRA2 – human
    
  • 5fht, 5m3o, 5tny, 5tnz, 5to0, 5to1, 5wyn – hPRO HTRA2 (mutant)
    
  • 1toc – PRO – bovine
    
  • 3s9a, 3s9b – RvPRO – Siamese Russell’s viper
    
  • 3s9c, 3sbk – RvPRO + human factor V polypeptide
    
  • 1po0, 1op2 – PRO – Chinese moccasin
    
  • 1qy8 – SaPRO
    
  • 1mbm – PRO – equine arteritis virus
    
  • 1dbi – PRO – Bacillus
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  • 1ga1, 1ga4, 1ga6, 1nlu – PsPRO + iodotyrostatin fragment – Pseudomonas
    
  • 6m8w, 6m8y, 6m8f, 6m9c, 6m9d - PsPRO + polypeptide inhibitor
    
  • 1s2n, 1sh7 – PRO – Vibrio
    
  • 2sfa – PRO – Streptomyces fradiae
    
• Astacin
  • 1ast – Ast – crayfish
    
  • 6saz, 6ht9 – Ast + fetuin-B
    
  • 1qjj – Ast + peptide inhibitor
    
  • 1qji – Ast + inhibitor
    
  • 1iaa, 1iab, 1iac, 1iad, 1iae – Ast + metal ion
    
  • 3lq0 – Pro-Ast (mutant)