1cvr
Crystal structure of the Arg specific cysteine proteinase gingipain R (RGPB)Crystal structure of the Arg specific cysteine proteinase gingipain R (RGPB)
Structural highlights
FunctionCPG2_PORGI Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Its proteolytic activity is a major factor in both periodontal tissue destruction and in bacterial host defense mechanisms. Activates complement C3 and C5 (By similarity). Evolutionary ConservationCheck, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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