7udc

cryo-EM structures of a synaptobrevin-Munc18-1-syntaxin-1 complex class1cryo-EM structures of a synaptobrevin-Munc18-1-syntaxin-1 complex class1

Structural highlights 7udc is a 3 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [STXB1_RAT] May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions. See Also Syntaxin 3D structures Syntaxin-binding protein

spinqualitylabelsall models 7udc, resolution 3.70Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image