Crystal structure of Alanyl-tRNA Synthetase from Pyrococcus horikoshii OT3Crystal structure of Alanyl-tRNA Synthetase from Pyrococcus horikoshii OT3

Structural highlights

1v4p is a 3 chain structure with sequence from 'pyrococcus shinkaii'. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Activity:Alanine--tRNA ligase, with EC number 6.1.1.7
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

[ALAXS_PYRHO] Functions in trans to edit the amino acid moiety from mischarged charged Ser-tRNA(Ala). Has little activity against Gly-tRNA(Ala).

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1v4p, resolution 1.45Å

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OCA