Thrombin 3D Structures

3D Structures of thrombin3D Structures of thrombin

Updated on 19-August-2024 - For a general description of the protein see Thrombin

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• Thrombin
  • 3gic, 3r3g - hThr HC + LC - human
    
  • 2od3, 3jz1, 3jz2, 6pxj, 6pxq - hThr HC + LC (mutant)
    
  • 7sr9 - hThr HC (mutant) + LC (mutant)
    
  • 1jou, 1sg8, 1sgi, 2a0q, 3ee0, 3qgn, 4rkj, 5jdu, 6pxq, 6pxj, - hThr HC (mutant) + LC
    
  • 2hnt– hThr-γ HC + LC
    
  • 3pmb - bThr HC + LC – bovine
    
  • 2ocv - mThr HC + LC - mouse
    
  • 3edx, 3hk3, 3hk6 - mThr HC (mutant) + LC
    
• Thrombin complexes with small molecule
  • 1abj, 1bhx, 1ppb, 6z48, 8ase - hThr HC + LC + inhibitor
    
  • 4rn6 - hThr HC (mutant) + inhibitor
    
  • 3dd2 - hThr HC + LC + RNA
    
  • 1hao, 1hap, 1hut, 3qlp, 4dih, 4lz1, 4lz4]], 6z8w, 6z8x, 7ntu, 7zkl, 7zkm, 7zkn, 7zko, 8bw5 - hThr HC + LC + aptamer
    
  • 3bf6 - hThr HC + LC + suramin
    
  • 1xmn - hThr HC + LC + heparin
    
  • 2h9t - hThr HC + LC + suramin + PPACK
    
  • 1z8i, 1z8j - hThr HC + LC (mutant) + PPACK
    
  • 1b7x, 1sfq, 1shh, 1thp, 2thf, 2pgq,4rko - hThr HC (mutant) + LC + PPACK
    
  • 1ook, 6v64 - hThr HC + LC + PPACK
    
  • 6gwe, 6t7h - hThr HC + LC + macrocycle
    
  • 5cmx, 5ew1, 5ew2 - hThr HC + LC + DNA
    
  • 5do4 - hThr HC + LC + RNA
    
  • 2hpp, 2hpq - hThr HC + LC + PThr residues 214-292 + PPACK
    
  • 3pma – bThr HC + LC residues 336-364 + sucrose octasulfate
    
  • 1uvs, 1uvt, 1uvu - bThr HC + LC + inhibitor
    
  • 1etr, 1ets, 1ett – bThr-ε HC + LC + inhibitor
    
• Thrombin complexes with peptide
  • 5gim - hPThr HC + LC + peptide
    
  • 3hkj - hThr HC (mutant) + LC + proteinase-activated receptor 1 peptide
    
  • 1de7 - hThr HC + LC + factor XIII activation peptide
    
  • 1fph - hThr HC + LC + fibrinogen peptide
    
  • 3bv9 - hThr HC (mutant) + LC + peptide inhibitor
    
  • 1dlt, 1eb1, 1h8d, 1h8i, 1hbt, 2a2x, 3u8t - hThr HC + LC + peptide inhibitor
    
  • 1eoj, 1eol, 1g37, 1nrn, 1nro, 1nrp, 1nrq, 1nrr, 1nrs - hThr HC + peptide inhibitor
    
  • 1hlt - hThr HC + LC + thrombomodulin peptide
    
  • 3qdz - hThr HC (mutant) + LC + PAR4 peptide
    
  • 4ch2, 4ch8 - hThr HC + LC + platelet glycoprotein IB α chain peptide
    
  • 2ank, 3po1 - hThr HC + LC + peptide + inhibitor
    
  • 1dlk - bThr HC + LC + peptide inhibitor
    
  • 1bbr, 1ycp – bThr-ε HC + LC + fibrinogen peptide
    
  • 1ucy - bThr HC + LC + fibrinogen peptide
    
  • 3hki - mThr HC (mutant) + LC + proteinase-activated receptor 1 peptide
    
  • 2pux - mThr HC + LC + proteinase-activated receptor 3 peptide
    
  • 2pv9 - mThr HC (mutant) + LC + proteinase-activated receptor 4 peptide
    
  • 1dm4 - mThr HC (mutant) + LC + fibrinogen peptide
    
• Thrombin complexes containing hirudin
  • 1a3b, 1a3e, 1ype, 1a46, 1a4w, 1a5g, 1a61, 1ad8, 1ae8, 1afe, 1aht, 1ai8, 1aix, 1awf, 1awh, 1ay6, 1b5g, 1ba8, 1bb0, 1bcu, 1bmm, 1bmn, 1c1u, 1c1v, 1c1w, 1c4u, 1c4v, 1c4y, 1c5n, 1c5o, 1ca8, 1d3d, 1d3p, 1d3q, 1d3t, 1d4p, 1fpc, 1ghv, 1ghw, 1ghx, 1ghy, 1qj1, 1gj4, 1gj5, 1qj6, 1qj7, 1kts, 1ktt, 1lhc, 1lhd, 1lhe, 1lhf, 1lhg, 1mu6, 1mu8, 1mue, 1nzq, 1o0d, 1o2g, 1oyt, ,1qhr, 1qur, 1riw, 1tbz, 1uma, 1vzq, 1w7g, 1way, 1wbg, 1ypg, 1ypj, 1ypk, 1ypl, 1ypm, 2anm, 2bdy, 2bvr, 2bvs, 2bvx, 2bxt, 2bxu, 2c8w, 2c8x, 2c8y, 2c8z, 2c90, 2c93, 2cf8, 2cf9, 2feq, 2fes, 2gde, 2jh0, 2jh5, 2jh6, 2pks, 2r2m, 2uuj, 2uuk, 2v3h, 2v3o, 2w7g, 2zc9, 2zda, 2zdv, 2zf0, 2zff, 2zfp, 2zfq, 2zfr, 2zg0, 2zgb, 2zgx, 2zhe, 2zhf, 2zhq, 2zhw, 2zi2, 2ziq, [[[2znk]], [2zo3]], 3biu, 3biv, 3c27, 3d49, 3da9, 3dhk, 3dt0, 3dux, 3egk, 3eq0, 3ldx, 3p17, 3qto, 3qtv, 3qwc, 3qx5, 3rlw, 3rly, 3rm0, 3rm2, 3rml, 3rmm, 3rmn, 3rmo, 3si3, 3si4, 3sha, 3shc, 3sv2, 3t5f, 3u98, 3u9a, 3uwj, 4e7r, 4loy, 6eo8, 6eo9, 6gbw, 6zgo - hThr HC + LC + hirudin peptide + inhibitor
    
  • 7ac9 – hThr HC + LC + hirudin peptide + Arg
    
  • 1d6w, 1d9i, 1doj, 1dwb, 1dwc, 1dwd, 1dwe, 1qbv, 1tmu, 1nm6, 1nt1, 1sl3, 1ta2, 1ta6, 1xm1, 1z71, 1zgi, 1zgv, 1zrb, 4baq, 4bao, 4ban, 4ud9, 4udw, 4ue7, 4ueh, 4ufd, 4ufe, 4uff, 4ufg, 4yes, 5a2m, 5af9, - hThr HC + hirudin peptide + inhibitor
    
  • 1a2c, 1hdt, 1ny2, 1tmt, 1tmb, 1tom, 3u8o, 3u8r, 7kme, 8kme - hThr HC + LC + hirudin peptide + peptide inhibitor
    
  • 3hat - hThr HC + LC + hirudin peptide + fibrinogen peptide
    
  • 1abi, 1c5l, 1hgt, 1hxe, 1hxf, 1ihs, 1iht, 1no9, 1thr, 1ths, 1vr1, 2hgt, 2pw8, 2uuf, 3htc, 3utu, 4ayv, 4ayy, 4az2, 4htc, 4thn, 5gds - hThr HC + LC + hirudin peptide
    
  • 3vxe, 3vxf - hThr HC + LC + bivalirudin peptide
    
  • 4mlf - hThr HC (mutant) + LC + hirudin peptide
    
  • 5mls, 5mjt, 5mm6 - hThr HC (mutant) + LC + hirudin peptide + inhibitor
    
  • 1hrt, 1vit - bThr HC + LC + hirudin peptide
    
• Thrombin complex with protein
  • 2a45 - hThr HC + LC + fibrinogen α, β, γ chains
    
  • 1tb6 - hThr HC + LC (mutant) + antithrombin
    
  • 2b5t - hThr HC (mutant) + LC + antithrombin III (mutant)
    
  • 4dt7 - hThr HC (mutant) + LC + vitamin K-dependent protein C peptide
    
  • 1jmo - hThr HC (mutant) + LC + heparin cofactor II
    
  • 4dy7 - hThr HC (mutant) + LC + glia-derived nexin
    
  • 1e0f - hThr HC + LC + haemadin
    
  • 4boh - hThr HC + LC + madanin
    
  • 4e05, 4e06 - hThr HC + LC + anophelin
    
  • 1dx5 - hThr HC + LC + thrombomodulin
    
  • 3p6z, 3p70 - hThr HC + LC + coagulation factor V
    
  • 7mj5 - hThr HC + LC + XC-43
    
  • 7phx - hThr HC + LC + tsetse coagulation inhibitor
    
  • 3pmh - hThr HC + LC + platelet glycoprotein IB α chain
    
  • 3b23 - hThr HC + LC + variegin
    
  • 1id5 - hThr HC + LC + ecotin
    
  • 6tkh, 6tki, 6tkj - hThr HC + LC + tsetse Thr inhibitor
    
  • 5e8e - hThr HC + LC + antibody
    
  • 1nu7, 2a1d – bThr HC + LC + staphylocoagulase
    
  • 1avg - bThr HC + LC + triabin
    
  • 1bth - bThr HC (mutant) + LC (mutant) + BPTI
    
  • 1toc - bThr HC + LC + ornithodorin
    
  • 1tbq, 1tbr - bThr HC + LC + rhodniin
    
• Prothrombin
  • 2afq, 3u69 - hPThr HC + LC
    
  • 3s7h, 3s7k, 6p9u – hPThr HC + LC (mutant)
    
  • 1rd3, 1tq0, 2gp9, 2pgb, 3bei, 4h6s, 4h6t, 4hzh, 6bjr, 6c2w - hPThr HC (mutant) + LC
    
  • 1mh0, 4nzq, 4o03 - hPThr HC (mutant)
    
  • 1nl1, 1nl2, 2pf1, 2pf2, 2spt – bPThr residues 1-156
• Prothrombin complexes
  • 6cym - hPThr HC + LC + inhibitor
    
  • 3bef, 3lu9 - hPThr HC + LC (mutant) + proteinase-activated receptor 1 peptide
    
  • 1sr5 - hPThr HC + LC + antithrombin III
    
  • 3f68 - hPThr HC residues 364-622 + LC residues 328-363 + hirudin peptide
    
  • 1jwt, 3c1k - hPThr HC + inhibitor
    
  • 4hfp - hPThr HC (mutant) + LC + inhibitor
    
  • 1tq7 - hPThr HC (mutant) + LC + PPACK
    
  • 1g30, 1g32, 1k21, 1k22, 1o5g, 1sb1, 1t4u, 1t4v, 3tu7, 4lxb, 5jfd, 5jzy, 5lce, 6eo8, 6eo9 6fjt, 6gbw, 6hsx, 6i51, 6rot, 6t3m, 6t3q, 6t4a, 6t52, 6t53, 6t54, 6t55, 6t56, 6t57, 6t89, 6t8a, 6tdt, 6y02, 6y9h, 6yb6, 6yhg, 6yhj, 6ymp, 6yn3, 6yqv, 6ysj, 6ysx, 6zug, 6zuh, 6zun, 6zuu, 6zuw, 6zux, 6zv7, 6zv8 - hPThr HC + LC + hirudin peptide + inhibitor
    
  • 4ax9 - hPThr HC + LC + hirudin peptide
    
  • 1twx - hPThr HC (mutant) + LC + hirudin peptide
    
  • 2hwl - hPThr HC (mutant) + LC + fibrinogen γ’ peptide
    
  • 4dii, 4i7y, 6eo6, 6eo7, 6evv, 6gn7, 6z8v - hPThr HC + LC + DNA aptamer
    
  • 7a0d, 7a0e, 7a0f - bPThr + hirudin peptide
    
• Prothrombin complex with protein
  • 1p8v - hPThr HC + LC + platelet glycoprotein IB α chain
    
  • 3gis - hPThr HC residues 364-622 (mutant) + LC residues 315-363 + thrombomodulin
    
  • 3b9f - hPThr HC (mutant) + LC + protein C inhibitor
    
  • 2ody - hPThr HC + LC + boophilin
    
  • 5nhu - hPThr HC + LC + CE5 anticoagulant
    
  • 5l6n - hPThr HC + LC + madanin
    
  • 6tkg, 6tkl - hPThr HC + LC + tsetse Thr inhibitor
    
• Prethrombin-1 residues 199-622
  • 3nxp - hThr
• Prethrombin-2 residues 328-622
  • 6v5t – hThr
    
  • 1nu9 – hThr + staphylocoagulase
    
  • 1mkw, 1mkx – hThr + bThr HC + LC
    
  • 1hag, 1hah – hThr + hirudin peptide
    
  • 1hai – hThr + inhibitor
    
  • 3sqe, 3sqh - hThr (mutant)
    
  • 3k65 - hThr HC residues 315-622 (mutant) + LC residues 199-314
    
• Meizothrombin
  • 3e6p – hMthr HC 364-622 + LC 206-363
  • 1a0h – bMThr HC 367-625 + LC 208-366
• Saxthrombin
  • 3s69 – Thr – Gloydis saxatilis