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Structure of the dihydrofolate reductase (folA) from Coxiella burnetii in complex with methotrexateStructure of the dihydrofolate reductase (folA) from Coxiella burnetii in complex with methotrexate
Structural highlights
FunctionQ83AB2_COXBU Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.[PIRNR:PIRNR000194] See Also |
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