3tq9

Structure of the dihydrofolate reductase (folA) from Coxiella burnetii in complex with methotrexateStructure of the dihydrofolate reductase (folA) from Coxiella burnetii in complex with methotrexate

Structural highlights

3tq9 is a 1 chain structure with sequence from Coxiella burnetii. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2.3Å
Ligands:	,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

Q83AB2_COXBU Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.[PIRNR:PIRNR000194]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

3tq9

Structure of the dihydrofolate reductase (folA) from Coxiella burnetii in complex with methotrexateStructure of the dihydrofolate reductase (folA) from Coxiella burnetii in complex with methotrexate

Structural highlights

Function

See Also

Contents

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)